Promethazine codeine syrup - An Overview

Promethazine codeine syrup - An Overview

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Promethazine with codeine syrup is indicated with the short-term aid of coughs and higher respiratory signs or symptoms connected to allergy or perhaps the common chilly.

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Codeine: A examine in rats and rabbits noted no teratogenic influence of codeine administered in the course of the duration of organogenesis in doses ranging from five to 120 mg/kg. From the rat, doses for the one hundred twenty-mg/kg amount, in the harmful assortment for your Grownup animal, had been connected to a rise in embryo resorption at some time of implantation.

When specified concomitantly with promethazine, the dose of barbiturates should be minimized by at least a single-50 %, and the dose of narcotics really should be reduced by a single-quarter to 1-50 %. Dosage need to be individualized. Too much quantities of promethazine HCl relative into a narcotic may well bring about restlessness and motor hyperactivity within the client with soreness; these indicators commonly disappear with adequate Charge of the pain.

When useful for an prolonged time, this medication might not get the job done at the same time and should demand various dosing. Speak with your health practitioner if this medication stops Performing nicely.

However it helps A lot of people, this medication features a chance for abuse and may often bring about addiction. This chance might be bigger Should you have a compound use condition (such as overuse of or dependancy to medicines/Alcoholic beverages).

In animal replica reports, codeine administered by the oral path to Expecting rats during the period of organogenesis increased resorptions and decreased fetal weights in a dose close to twenty five periods the utmost encouraged human dose (MRHD) while in the existence of maternal toxicity (see Info).

People really should be suggested to evaluate promethazine with codeine syrup with an correct measuring device. A home teaspoon isn't an correct measuring product and may lead to overdosage, specially when a fifty percent a teaspoon is calculated.

Phenothiazines are linked to dystonic reactions, significantly in pediatric individuals which have an acute illness affiliated with dehydration. Paradoxical reactions, like dystonia, torticollis, tongue protrusion, hyperexcitability, and abnormal movements are actually claimed in individuals subsequent one administration of promethazine. Discontinue Promethazine HCl and Codeine Phosphate Oral Solution if a paradoxical response happens.

Postmarketing situations of respiratory depression, such as fatalities happen to be claimed with use of promethazine in pediatric patients.

g., amiodarone, quinidine) may possibly end in a rise in codeine plasma concentrations along with a minimize in Lively metabolite morphine plasma focus which could bring about an analgesic efficacy reduction or signs and symptoms of opioid withdrawal.

Breathing problems (respiratory melancholy)that can lead to death and opioid withdrawal can happen Promethazine codeine syrup if You begin using or cease getting other medicines whilst having Promethazine Hydrochloride and Codeine Phosphate Oral Resolution, including:

As a consequence of inconsistencies among the drug labels on DailyMed plus the capsule illustrations or photos furnished by RxImage, we no more Screen the RxImage capsule photos affiliated with drug labels.

When physicians prescribe codeine-that contains prescription drugs, they should choose the lowest helpful dose with the shortest timeframe and will advise their clients about these challenges plus the indications of morphine overdose (see PRECAUTIONS - Nursing Mothers).